Is the active ingredient. formulations may also contain inactive ingredients (excipients) that vary depending on the brand and dosage form (tablet, etc.). always check the product label for a complete list of ingredients.
Treatment of type 2 diabetes mellitus in adults, often in combination with other diabetes medications such as metformin or insulin.
Improves glycemic control by increasing incretin hormone levels.
Januvia 25mg Tab (Sitagliptin) is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 enzymes break down incretin hormones (GLP-1 and GIP) that stimulate insulin release and suppress glucagon secretion. By inhibiting DPP-4, sitagliptin increases the levels of these incretins, leading to better blood sugar control.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Discard any expired medication according to local guidelines.
Dosage varies depending on individual needs and other medications being taken. Always follow your doctor's prescription instructions.
Typically taken once daily, with or without food.
Headache
Nasopharyngitis (common cold)
Upper respiratory tract infection
Nausea
Diarrhea
Hypersensitivity reactions (rare but serious)
Pancreatitis (rare but serious)
Moderate alcohol consumption may be permissible, but excessive alcohol intake should be avoided as it can negatively impact blood sugar control and interact with other medications.
Sitagliptin typically does not impair alertness or cognitive function; however, individuals should monitor their response to the medication and avoid driving or operating machinery if they experience side effects such as dizziness or lightheadedness.
Use during pregnancy and breastfeeding should be carefully considered by your doctor. The potential risks and benefits need to be evaluated individually.
Sitagliptin is not generally approved for use in children.
Dosage adjustment may be necessary for individuals with kidney impairment.
Dosage adjustment may be necessary for individuals with liver impairment.
Your doctor or pharmacist
The medication's package insert
Reputable medical websites and databases (e.g., FDA, reputable medical journals)
