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Janumet 50/1000mg Tab
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Marketer
Msd Pharmaceuticals Pvt Ltd
Composition
Sitagliptin (50mg) + Metformin (1000mg)
100% Genuine Products
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Contact Less Delivery
Fully Sanitized Packing
About Janumet 50/1000mg Tab
Janumet 50/1000mg Tab (Sitagliptin + Metformin) is a combination medication used to control blood sugar levels in adults with type 2 diabetes. It works by increasing insulin release and improving insulin sensitivity. Common side effects include nausea, diarrhea, and headache. This medication requires careful monitoring, especially for individuals with kidney or liver problems. Always follow your doctor's instructions and report any concerning side effects immediately.
Ingredients of Janumet 50/1000mg Tab

    Sitagliptin

    A dipeptidyl peptidase-4 (dpp-4) inhibitor that helps the body release more insulin when needed and reduces the production of excess glucose.

    Metformin

    A biguanide that lowers blood glucose levels by decreasing glucose production in the liver and improving insulin sensitivity.

Direction for Use of Janumet 50/1000mg Tab

    Treatment of type 2 diabetes mellitus in adults, particularly when metformin alone is insufficient to control blood sugar levels.

How Janumet 50/1000mg Tab Works

Sitagliptin works by inhibiting the DPP-4 enzyme, which normally breaks down incretins (hormones that stimulate insulin release). By inhibiting DPP-4, sitagliptin increases incretin levels, leading to improved glucose control. Metformin works by reducing glucose production in the liver, increasing insulin sensitivity in muscle tissue, and decreasing glucose absorption in the gut. The combination provides a synergistic effect on blood glucose management.

Storage and Handling of Janumet 50/1000mg Tab

Store at room temperature, below 30°C (86°F), in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Dosage of Janumet 50/1000mg Tab

    Dosage should be determined by a healthcare professional based on individual needs and response to treatment.

    Generally, it is recommended to start with a low dose and gradually increase it as needed.

    Always follow your doctor's instructions carefully and do not alter your dosage without consulting them.

Side effects of Janumet 50/1000mg Tab

Less Common: Hypoglycemia (low blood sugar), allergic reactions (rash, itching, swelling), lactic acidosis (rare but serious).

Note: This is not an exhaustive list. Consult your doctor or pharmacist if you experience any concerning side effects.

    Common: Nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, upper respiratory tract infection.

Safety Consideration or Warnings
    Alcohol Consumption

    Alcohol consumption may increase the risk of hypoglycemia and lactic acidosis. Limit alcohol intake while taking this medication.

    Driving or Operating Machinery

    May cause dizziness or lightheadedness. Avoid driving or operating machinery if affected.

    Pregnant & Breastfeeding Women

    Not recommended during pregnancy. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

    Children

    Not indicated for use in children.

    Kidney

    Caution is advised in patients with kidney disease. Dosage adjustment may be necessary.

    Liver

    Caution is advised in patients with liver disease. Dosage adjustment may be necessary.

References

    Please consult your doctor or pharmacist for specific references and further information regarding the medication.

Last Updated On 14 May. 2025 | 11:48 PM (IST)
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