Prescription Required.
Methotrexate is the active ingredient in this medication.It is available in various forms like tablets, injections, and oral solutions.
Rheumatoid arthritis
Psoriasis
Crohn's disease
Ulcerative colitis
Certain types of cancer (e.g., leukemia, lymphoma)
Ectopic pregnancy (offlabel use)
Imutrex 7.5mg Tab (Methotrexate) is an anti-metabolite that inhibits the production of dihydrofolate reductase, an enzyme essential for DNA synthesis. This slows down the growth of rapidly dividing cells, including cancerous cells and immune system cells involved in inflammatory conditions.
Store methotrexate at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.
Dosage and administration vary depending on the specific condition being treated and the individual patient.
Your healthcare provider will determine the appropriate dosage and frequency for you.
Methotrexate can be taken orally, injected into a vein, or injected into a muscle.
Follow your doctor's instructions carefully and take the medication exactly as prescribed.
Nausea and vomiting
Diarrhea
Mouth sores
Hair loss
Liver damage
Bone marrow suppression
Increased risk of infections
Lung problems
Severe allergic reactions
Alcohol consumption can increase the risk of liver damage when taking methotrexate. Avoid excessive alcohol intake.
Methotrexate can cause dizziness, drowsiness, and fatigue. Avoid driving or operating machinery until you know how this medication affects you.
Methotrexate is a teratogen, meaning it can cause birth defects. It should not be used during pregnancy. It is also not recommended for breastfeeding women, as it can pass into breast milk.
Methotrexate is not typically prescribed for children unless other treatments have failed.
People with kidney problems may need to take a lower dose of methotrexate.
People with liver problems may need to take a lower dose of methotrexate and require close monitoring.
National Institutes of Health (NIH)
U.S. Food and Drug Administration (FDA)
The American College of Rheumatology (ACR)
The National Psoriasis Foundation (NPF)
