Prescription Required.Why?
Imatinib mesylate is the active ingredient in the medication.It belongs to a class of drugs called tyrosine kinase inhibitors.
Chronic myeloid leukemia (CML) in chronic phase, accelerated phase, or blast crisis.
Philadelphia chromosomepositive acute lymphoblastic leukemia (Ph+ ALL) in adults and children.
Gastrointestinal stromal tumors (GISTs) that are unresectable or metastatic.
Certain types of advanced systemic mastocytosis.
Imatinib Mesylate Tablets Ip 400mg (Imatinib Mesylate) works by blocking the activity of a specific protein called BCR-ABL tyrosine kinase. This protein is abnormally active in CML and Ph+ ALL, and it helps cancer cells grow and spread. By blocking this protein, imatinib mesylate helps to slow down or stop the growth of cancer cells.
Store imatinib mesylate at room temperature, between 20°C and 25°C (68°F and 77°F). Keep it in its original container, tightly closed, and away from light and moisture.
The dosage of imatinib mesylate will be determined by your doctor based on your individual needs and medical condition.
It is typically taken orally, once daily with or without food.
It is important to take imatinib mesylate exactly as prescribed by your doctor and to complete the full course of treatment, even if you feel better.
Nausea
Vomiting
Diarrhea
Muscle aches
Fatigue
Swelling in the legs or ankles
Skin rash
Headache
Fluid retention
It is generally recommended to avoid alcohol while taking imatinib mesylate as it can potentially increase the risk of side effects.
Imatinib mesylate may cause fatigue or dizziness, which can affect your ability to drive or operate machinery. Do not drive or operate machinery if you experience these symptoms.
Imatinib mesylate can harm an unborn baby. It is not recommended for pregnant women. It is also not recommended for breastfeeding mothers as it can pass into breast milk.
Imatinib mesylate is used in children with certain types of leukemia, but it is not safe for all children. Your doctor will carefully consider the risks and benefits of treatment for your child.
Imatinib mesylate is primarily eliminated from the body through the kidneys. If you have kidney problems, your doctor may need to adjust your dose.
Imatinib mesylate can also affect the liver. Your doctor may monitor your liver function during treatment.
https://www.fda.gov/drugs/resources-information-approved-drugs/gleevec-imatinib-mesylate
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/imatinib
https://www.mayoclinic.org/diseases-conditions/chronic-myeloid-leukemia/diagnosis-treatment/drc-20353811
