Indomethacin

Is the active pharmaceutical ingredient (api).

Treatment of mild to moderate pain, including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

Acute gouty arthritis.

Closure of patent ductus arteriosus in premature infants (under strict medical supervision).

Imacin Sr 75mg Cap (Indomethacin) is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, inflammatory mediators responsible for pain, fever, and inflammation. It achieves this by inhibiting cyclooxygenase (COX) enzymes, COX-1 and COX-2.

Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Discard any unused medication after the expiry date.

Dosage varies depending on the condition being treated and the patient's individual needs. Always follow your doctor's instructions precisely.

Available in various forms including capsules, tablets, and suppositories.

Do not exceed the prescribed dosage.

Gastrointestinal issues (nausea, vomiting, heartburn, stomach pain, ulceration, bleeding)

Headache

Dizziness

Fluid retention

Increased blood pressure

Allergic reactions (rash, itching, swelling)

Liver damage (rare but serious)

Kidney problems (rare but serious)

Alcohol Consumption

Alcohol may increase the risk of gastrointestinal bleeding and other side effects. Avoid alcohol consumption while taking indomethacin.



While Driving or operating Machinery

Indomethacin may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how this medication affects you.



Pregnant & Breastfeeding Women

Indomethacin should generally be avoided during pregnancy, especially in the late stages, and breastfeeding due to potential risks to the fetus or infant. Consult your doctor.



Children

Use in children is generally restricted to specific conditions (e.g., closure of patent ductus arteriosus) under strict medical supervision due to potential side effects.



Kidney

Indomethacin can affect kidney function, particularly in patients with pre-existing kidney disease. Regular monitoring may be necessary.



Liver

Indomethacin can affect liver function, regular monitoring for liver dysfunction is recommended especially in patients with pre-existing liver disease.

Your doctor or pharmacist.

The prescribing information provided with your medication.

Reputable medical websites (e.g., Mayo Clinic, NHS).