L-Ornithine-L-Aspartate

L-Ornithine: A non-essential amino acid involved in the urea cycle, aiding in ammonia detoxification.L-Aspartate: An amino acid that plays a crucial role in numerous metabolic processes, including the urea cycle.

Treatment of hepatic encephalopathy (liver failurerelated brain dysfunction)

Reduction of hyperammonemia (elevated blood ammonia levels)

Support for liver function in certain conditions (often used adjunctively)

Hepamerz Infusion 10ml (L-Ornithine-L-Aspartate) (LOLA) works primarily by enhancing the urea cycle, facilitating the conversion of ammonia (a toxic byproduct of protein metabolism) into urea, which is then excreted by the kidneys. This helps lower ammonia levels in the blood, thus reducing the risk and severity of hepatic encephalopathy symptoms. The exact mechanism of action may vary depending on the specific condition being treated.

Store in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

Dosage varies widely depending on the indication, patient's condition, and physician's recommendations.

It's crucial to follow the prescribed dosage and administration instructions exactly as provided by your healthcare professional.

Oral administration is common (tablets or capsules).

Gastrointestinal upset (nausea, vomiting, diarrhea)

Mild allergic reactions (rash, itching)

Headache

Drowsiness

Alcohol Consumption

Alcohol consumption may exacerbate liver damage and should be avoided or strictly limited, especially during treatment with LOLA.



While Driving or Operating Machinery

Drowsiness is a potential side effect; avoid driving or operating heavy machinery if experiencing drowsiness.



Pregnant & Breastfeeding Women

Use during pregnancy and breastfeeding should only be considered under strict medical supervision due to limited data on safety.



Children

Dosage and safety in children require careful consideration and should be determined by a physician.



Kidney

Patients with severe kidney impairment may require dosage adjustment due to the kidneys' role in urea excretion. Consult your doctor.



Liver

While used to treat liver conditions, patients with severe liver disease may require careful monitoring during LOLA therapy.

Refer to your physician or pharmacist for specific product information and citations.