Acyclovir

Acyclovir is the active ingredient in many medications.Specific formulations may contain additional inactive ingredients like fillers, binders, and coatings which vary depending on the brand and dosage form (tablet, cream, ointment).

Treatment of herpes simplex virus (HSV) infections (oral, genital, and neonatal)

Treatment of varicellazoster virus (VZV) infections (chickenpox and shingles)

Suppression of recurrent HSV infections

Treatment of cytomegalovirus (CMV) infections in immunocompromised individuals (e.g., those with HIV/AIDS) often requires higher doses and intravenous administration.

Helovir 5% Cream (Acyclovir) is a nucleoside analogue. It inhibits viral DNA polymerase, preventing viral replication. The virus incorporates acyclovir into its DNA, leading to chain termination and ultimately inhibiting viral replication. It's more effective against actively replicating viruses.

Store acyclovir at room temperature, away from moisture and direct sunlight. Discard any expired medication according to local regulations. Keep out of reach of children.

Dosage varies widely depending on the type of infection, severity, and patient factors (age, kidney function).

Always follow your doctor's or pharmacist's instructions precisely.

Oral medications are usually taken multiple times daily.

Topical creams and ointments should be applied directly to affected areas as directed.

Intravenous administration is used for severe or systemic infections.

Nausea

Vomiting

Diarrhea

Headache

Fatigue

Rash

Itching

Neurological effects (rare, but can include confusion, seizures, and tremors)

Alcohol Consumption

Avoid excessive alcohol consumption as it can potentially worsen side effects or interact with other medications.



While Driving or operating Machinery

Acyclovir may cause drowsiness or dizziness; avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Discuss the use of acyclovir with your doctor if you are pregnant or breastfeeding. The benefits must be weighed against potential risks.



Children

Dosage adjustments may be necessary for children. Always follow your doctor's instructions.



Kidney

Acyclovir can be hard on the kidneys, especially at high doses. Kidney function should be monitored, especially in those with pre-existing kidney disease.



Liver

Generally well-tolerated by the liver, however, liver function should be monitored in those with pre-existing liver disease.

Your doctor or pharmacist

The medication's package insert

Reputable medical websites (e.g., Mayo Clinic, NHS)