Gliclazide

A sulfonylurea drug that helps the pancreas release more insulin, lowering blood sugar levels.

Pioglitazone

A thiazolidinedione drug that improves insulin sensitivity by making cells more responsive to insulin.

Metformin

A biguanide drug that helps reduce the liver's production of glucose and improves insulin sensitivity.

Type 2 diabetes mellitus, especially when diet and exercise alone are not sufficient to control blood sugar levels.

May be used in combination with other diabetes medications, such as insulin.

This combination medication works by improving the body's ability to use insulin. Gliclazide stimulates insulin release from the pancreas, Pioglitazone makes cells more receptive to insulin, and Metformin reduces glucose production by the liver. These combined effects help lower blood sugar levels and improve glucose control in people with type 2 diabetes.

Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.

The dosage is usually determined by your doctor and will depend on your individual needs and response to the medication.

Take the medication as prescribed by your doctor, even if you feel well.

Do not skip doses, and avoid taking more than the prescribed amount.

Take the medication with food to minimize stomach upset.

It may take several weeks for the full effect of this medication to be seen.

Hypoglycemia (low blood sugar): This is a common side effect and may cause symptoms like dizziness, sweating, headache, and confusion. It is essential to know how to manage hypoglycemia and carry a fast-acting sugar source with you.

Weight gain: Pioglitazone can cause weight gain.

Gastrointestinal upset: Metformin can cause nausea, vomiting, diarrhea, and abdominal pain.

Liver problems: Rare but serious, can occur with pioglitazone.

Alcohol Consumption

Alcohol may increase the risk of hypoglycemia. Avoid excessive alcohol consumption.



While Driving or operating Machinery

Be cautious while driving or operating machinery, as hypoglycemia can cause drowsiness and dizziness.



Pregnant & Breastfeeding Women

This medication is generally not recommended during pregnancy and breastfeeding. Discuss the risks and benefits with your doctor.



Children

Not recommended for children under 18 years old.



Kidney

May need to be adjusted in patients with kidney disease. Monitor kidney function regularly.



Liver

Should be used cautiously in patients with liver disease. Monitor liver function regularly.

Please consult your doctor or pharmacist for further information about this medication.