A sulfonylurea drug that stimulates the pancreas to release more insulin.
A thiazolidinedione (tzd) that improves insulin sensitivity in the body's tissues.
A biguanide that reduces glucose production by the liver and improves insulin sensitivity.
Type 2 diabetes mellitus in adults when diet and exercise alone are insufficient to control blood sugar levels.
Specifically used in patients where a combination of these three drugs is deemed necessary by a healthcare professional based on individual needs and response to treatment.
This triple combination medication works synergistically to lower blood glucose levels. Gliclazide increases insulin secretion, pioglitazone enhances insulin sensitivity, and metformin decreases hepatic glucose production and improves insulin sensitivity. The combined effect leads to better glycemic control than using any single drug alone.
Store at room temperature (below 25°C), protect from moisture and light. Keep out of reach of children. Dispose of properly according to local regulations. Do not use after the expiry date.
Dosage is strictly individualized and determined by a physician based on blood glucose levels and patient response.
Always follow your doctor's instructions precisely. Do not adjust the dosage on your own.
Medication should be taken with meals to minimize gastrointestinal side effects.
Hypoglycemia (low blood sugar): Symptoms include sweating, dizziness, shakiness, and confusion.
Liver problems (rare but serious, requires monitoring).
Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain.
Weight gain (more likely with pioglitazone).
Fluid retention (more likely with pioglitazone).
Allergic reactions (rash, itching, swelling).
Alcohol consumption can increase the risk of hypoglycemia and should be limited or avoided.
Hypoglycemia can impair judgment and reaction time. Avoid driving or operating machinery if experiencing symptoms of low blood sugar.
Not recommended during pregnancy and breastfeeding. Consult your doctor about alternative treatments.
Not recommended for use in children.
Metformin should be used with caution or avoided in patients with kidney disease, as it can increase the risk of lactic acidosis.
Regular liver function tests are recommended, especially during the initial stages of treatment with pioglitazone.
Please consult your physician or pharmacist for complete information and latest updates on this medication. Refer to the patient information leaflet provided with your prescription.
