Prescription Required.Why?
A sulfonylurea drug that stimulates the pancreas to release more insulin.
A biguanide that improves insulin sensitivity and reduces glucose production in the liver.
Type 2 diabetes mellitus in adults, particularly when diet and exercise alone are insufficient to control blood sugar levels.
May be used as initial therapy or in combination with other antidiabetic medications.
Gliclazide increases insulin secretion from the pancreas, while metformin enhances insulin sensitivity at the cellular level and reduces hepatic glucose production. This combined action leads to improved blood glucose control.
Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Dosage is determined by the physician based on individual needs and response to therapy.
Typically, the medication is taken orally, with or without food, as directed by the prescribing doctor.
Dosage adjustments may be required based on blood glucose monitoring and kidney function.
Hypoglycemia (low blood sugar): Symptoms may include dizziness, sweating, shakiness, and confusion.
Lactic acidosis (rare but serious): Characterized by muscle pain, weakness, shortness of breath, and rapid heartbeat.
Gastrointestinal upset: Nausea, vomiting, diarrhea, abdominal pain.
Vitamin B12 deficiency (rare).
Allergic reactions (rash, itching, swelling).
Weight gain (possible)
Alcohol consumption should be limited or avoided, as it can increase the risk of hypoglycemia and lactic acidosis.
Patients should exercise caution, especially if experiencing hypoglycemia, as it can impair alertness and coordination.
Generally not recommended during pregnancy and breastfeeding. Consult with your doctor for alternative treatment options.
Not indicated for use in children.
Dose adjustment is necessary for patients with impaired kidney function. This medication is contraindicated in severe kidney disease.
Caution is advised in patients with liver disease. Regular monitoring of liver function may be necessary.
Consult your physician or pharmacist for detailed information and product monograph.
Reputable medical websites and journals (list specific references if possible, e.g., relevant clinical guidelines).
