Glimepiride

A sulfonylurea medication that helps your pancreas produce more insulin.

Metformin

A biguanide medication that lowers glucose production by your liver and improves your body's response to insulin.

Vitamin D3

A fat-soluble vitamin that helps your body absorb calcium and phosphorus, which are essential for bone health.

Type 2 diabetes mellitus: This combination medication is used to control blood sugar levels in adults with type 2 diabetes.

Vitamin D deficiency: Vitamin D3 is included in this formulation to address potential vitamin D deficiency, which is common in people with diabetes.

0 Glimepiride: Stimulates insulin release from the pancreas, leading to increased glucose uptake by cells and lowering blood sugar levels.1 Metformin: Suppresses hepatic glucose production, enhances insulin sensitivity, and improves glucose uptake by tissues.2 Vitamin D3: Promotes calcium absorption in the intestines, contributing to overall bone health and potentially influencing insulin sensitivity.

0

Store this medication at room temperature, away from moisture and direct sunlight.

1

Keep it out of reach of children and pets.

2

Do not use this medication after the expiration date printed on the label.

The dosage of this medication is individualized and determined by your doctor based on your condition, response to treatment, and other factors.

This medication is typically taken orally, usually once daily, with meals.

Do not adjust the dosage or stop taking this medication without consulting your doctor.

Hypoglycemia (low blood sugar): Common side effect, especially with higher doses or skipping meals. Symptoms include dizziness, sweating, hunger, and confusion.

Gastrointestinal upset: Nausea, vomiting, diarrhea, and stomach pain are possible side effects of metformin.

Other potential side effects: Headache, weight gain, fluid retention, and bone pain.

Skin reactions: Allergic reactions, such as rashes, itching, and hives, can occur.

Alcohol Consumption

Alcohol can increase the risk of hypoglycemia. Limit alcohol consumption while taking this medication.



While Driving or Operating Machinery

Hypoglycemia can impair concentration and alertness. Avoid driving or operating machinery if experiencing low blood sugar.



Pregnant & Breastfeeding Women

This medication is not recommended during pregnancy. Consult your doctor about the risks and benefits of using this medication during breastfeeding.



Children

This medication is not approved for use in children.



Kidney

Kidney impairment can affect the elimination of metformin. Dosage adjustments may be required.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018317s039lbl.pdf

https://www.ncbi.nlm.nih.gov/pubmed/11943738

https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/diagnosis-treatment/drc-20351199