Prescription Required.Why?
A sulfonylurea drug that stimulates the pancreas to release more insulin.
A biguanide drug that improves insulin sensitivity and reduces glucose production by the liver.
Type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.
Often used in patients who are insulinresistant.
Glimepiride enhances insulin secretion from the pancreas, while metformin primarily improves insulin sensitivity in peripheral tissues and reduces hepatic glucose production. Their combined action helps lower blood glucose levels more effectively than either drug alone.
Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Dosage should be determined by a physician based on individual needs and response to treatment.
Generally, the medication is taken orally, usually once or twice daily with meals.
Never adjust the dosage without consulting your doctor.
Weight gain (less common with metformin than with other diabetes medications)
Hypoglycemia (low blood sugar): Symptoms include sweating, trembling, dizziness, confusion, and weakness.
Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain.
Allergic reactions: Skin rash, itching, hives.
Alcohol can increase the risk of hypoglycemia and should be consumed in moderation or avoided entirely.
Hypoglycemia can impair alertness and reaction time. Avoid driving or operating machinery if experiencing hypoglycemia.
Use during pregnancy and breastfeeding is generally not recommended. Consult your doctor immediately.
Not typically indicated for use in children.
May need dosage adjustment or avoidance in patients with kidney disease. Regular kidney function monitoring is essential.
May need dosage adjustment or avoidance in patients with liver disease. Regular liver function monitoring may be necessary.
Consult your physician or pharmacist for detailed information.
Refer to the medication's package insert for complete prescribing information.
Check reputable medical websites such as the FDA or NHS website.
