Temozolomide

Is the active ingredient in this medication. it is a type of chemotherapy drug known as an alkylating agent.

Temozolomide is primarily used to treat a type of brain cancer called glioblastoma multiforme.

It may also be used to treat other types of brain tumors, such as anaplastic astrocytoma and oligodendroglioma.

It is sometimes used in combination with radiation therapy.

Glioz 100mg Cap (Temozolomide) works by damaging the DNA of cancer cells, which prevents them from growing and dividing. It is a prodrug, meaning it is converted into an active form in the body that can then kill cancer cells.

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Store temozolomide at room temperature, between 15°C and 30°C (59°F and 86°F).

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Keep it away from heat and moisture.

2

Protect it from light.

3

Do not store in the bathroom.

The dosage of temozolomide will be determined by your doctor, based on your individual needs.

It is typically taken orally, as capsules or tablets, with or without food.

The frequency and duration of treatment will depend on the type of cancer you have, the stage of the disease, and how well your body responds to treatment.

Your doctor will carefully monitor your progress during treatment and adjust the dose as needed.

Temozolomide can cause a variety of side effects, some of which may be serious.

Common side effects include:

Serious side effects can include:

Nausea and vomiting

Fatigue

Hair loss

Low blood cell counts (neutropenia, anemia, thrombocytopenia)

Skin rash

Liver problems

Kidney problems

Lung problems

Seizures

Second cancers

Alcohol Consumption

It is generally advisable to avoid alcohol consumption while taking temozolomide, as it can increase the risk of liver damage.



While Driving or Operating Machinery

Temozolomide can cause fatigue, dizziness, and other side effects that may impair your ability to drive or operate machinery safely. It is best to avoid these activities until you know how this medication affects you.



Pregnant & Breastfeeding Women

Temozolomide is known to be harmful to a developing fetus. It is strongly recommended to avoid getting pregnant during treatment. If you are breastfeeding, you should talk to your doctor about whether you should stop breastfeeding.



Children

Temozolomide is not approved for use in children.



Kidney

Temozolomide can damage the kidneys. Your doctor will monitor your kidney function during treatment.



Liver

Temozolomide can damage the liver. Your doctor will monitor your liver function during treatment.

National Cancer Institute (NCI): https://www.cancer.gov/

Food and Drug Administration (FDA): https://www.fda.gov/

Drug manufacturer's website (e.g., Teva Pharmaceuticals)