Glimepiride

A sulfonylurea drug that stimulates the pancreas to release more insulin.

Metformin

A biguanide that helps improve insulin sensitivity and reduces glucose production by the liver.

Voglibose

An alpha-glucosidase inhibitor that slows down the breakdown of carbohydrates in the gut, reducing post-meal glucose spikes.

Type 2 diabetes mellitus, particularly in patients who haven't achieved adequate glycemic control with metformin alone or other monotherapies.

Treatment of hyperglycemia (high blood sugar) in patients with type 2 diabetes.

This combination medication works synergistically. Glimepiride increases insulin secretion, metformin enhances insulin sensitivity and reduces hepatic glucose production, and voglibose inhibits carbohydrate digestion, leading to a more controlled blood glucose level.

Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Discard any unused medication after the expiration date.

Dosage should always be determined by a healthcare professional and individualized based on patient needs and response to therapy.

Typically, the combination is initiated at lower doses and gradually increased as needed.

Follow the specific instructions prescribed by your doctor carefully.

Hypoglycemia (low blood sugar): Symptoms include sweating, shakiness, dizziness, and confusion.

Lactic acidosis (rare but serious): Characterized by muscle pain, weakness, and shortness of breath (more common with Metformin).

Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain.

Allergic reactions: Rash, itching, swelling.

Weight gain.

Alcohol Consumption

Alcohol can increase the risk of hypoglycemia and lactic acidosis. Limit alcohol intake.



Driving or Operating Machinery

If hypoglycemia occurs, it can impair alertness and coordination. Avoid driving or operating machinery until your blood sugar is stable.



Pregnant & Breastfeeding Women

Generally not recommended during pregnancy or breastfeeding. Discuss with your doctor about alternative options.



Children

Not typically used in children.



Kidney

Dosage adjustment or alternative treatment may be necessary for patients with kidney impairment. Regular monitoring of kidney function is crucial.



Liver

Use with caution in patients with liver disease. Regular monitoring of liver function is important.

Consult your doctor or pharmacist for detailed information.

Refer to the official drug monograph for complete information on potential side effects and interactions.