Gliclazide

A sulfonylurea drug that stimulates the pancreas to release more insulin.

Metformin

A biguanide drug that improves insulin sensitivity and reduces glucose production by the liver.

Type 2 diabetes mellitus, particularly in patients who have not achieved adequate glycemic control with metformin alone.

Used when lifestyle modifications (diet and exercise) are insufficient to control blood sugar levels.

Gliclazide increases insulin secretion from the pancreas, while metformin enhances insulin sensitivity in peripheral tissues and reduces hepatic glucose production. The combination provides a synergistic effect in lowering blood glucose levels.

Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children. Discard expired medication properly.

Dosage should be determined by a healthcare professional based on individual needs and response to treatment.

Typically started at a low dose and gradually increased as needed.

Administered orally, usually with meals, to minimize gastrointestinal side effects.

Hypoglycemia (low blood sugar): Symptoms include dizziness, sweating, tremors, and confusion.

Lactic acidosis (rare but serious): Characterized by muscle pain, weakness, shortness of breath, and abdominal discomfort.

Gastrointestinal upset: Nausea, vomiting, diarrhea, abdominal pain.

Vitamin B12 deficiency (rare, longterm use)

Allergic reactions (rash, itching, swelling)

Alcohol Consumption

Alcohol consumption should be limited or avoided as it can increase the risk of hypoglycemia and lactic acidosis.



While Driving or operating Machinery

Patients experiencing hypoglycemia should avoid driving or operating machinery.



Pregnant & Breastfeeding Women

Generally not recommended during pregnancy or breastfeeding. Consult a doctor immediately.



Children

Not indicated for use in children.



Kidney

Should be used with caution in patients with impaired kidney function. Dosage adjustment may be necessary.



Liver

Should be used with caution in patients with impaired liver function. Dosage adjustment may be necessary.

Consult your doctor or pharmacist for detailed information and current prescribing information.

Refer to your medication's package insert for specific details.