Prescription Required.Why?
A dipeptidyl peptidase-4 (dpp-4) inhibitor that helps the body release more insulin when blood sugar is high.
A biguanide that improves insulin sensitivity and reduces glucose production by the liver.
A sulfonylurea that stimulates the pancreas to release more insulin.
Type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.
Used in patients who need a combination therapy to achieve optimal glycemic control.
This triple combination medication works synergistically to lower blood sugar. Sitagliptin enhances insulin secretion and reduces glucagon secretion. Metformin improves insulin sensitivity and decreases hepatic glucose production. Glimepiride stimulates insulin release from the pancreas.
Store at room temperature (below 30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Dosage should be determined by a healthcare professional based on individual needs and response.
Typically started at a lower dose and gradually increased as needed.
Always take with food to minimize gastrointestinal side effects.
Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain (more common with metformin).
Hypoglycemia (low blood sugar): Symptoms include dizziness, sweating, shaking, confusion.
Headache, upper respiratory infections.
Allergic reactions (rash, itching, swelling).
Alcohol can increase the risk of hypoglycemia and lactic acidosis. Limit alcohol intake.
Hypoglycemia can impair judgment and coordination. Avoid driving or operating machinery if experiencing symptoms.
Generally not recommended during pregnancy or breastfeeding. Consult a doctor for alternative options.
Not indicated for use in children.
Dose adjustment or contraindicated in patients with severe kidney disease. Regular kidney function monitoring may be needed.
Dose adjustment or contraindicated in patients with severe liver disease. Liver function monitoring may be needed.
Consult your physician or pharmacist for detailed prescribing information.
Package Insert of the specific medication formulation
