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A sulfonylurea medication that helps the pancreas produce more insulin.
A biguanide medication that lowers glucose production in the liver and improves insulin sensitivity.
A thiazolidinedione medication that enhances insulin sensitivity in the body's tissues.
Type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.
May be used in combination with other diabetes medications.
This drug combination works by improving the body's ability to use insulin effectively. Glimepiride stimulates the pancreas to produce more insulin, while metformin reduces glucose production in the liver and pioglitazone increases insulin sensitivity in tissues.
Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Dosage is individualized based on your needs and response to treatment.
Typically taken orally once daily, usually with breakfast or the first meal of the day.
Follow your doctor's instructions carefully.
Hypoglycemia (low blood sugar): Symptoms include sweating, dizziness, weakness, headache, and confusion.
Gastrointestinal upset: Nausea, vomiting, diarrhea, and abdominal pain.
Weight gain.
Fluid retention (edema).
Liver problems (rare).
Heart failure (rare).
Allergic reactions (rare).
Alcohol can increase the risk of hypoglycemia. Avoid excessive alcohol consumption.
Hypoglycemia can impair your ability to drive or operate machinery. Be cautious.
This drug is not recommended during pregnancy or breastfeeding. Consult your doctor.
This medication is not approved for use in children.
Kidney problems can affect how this medication works. Consult your doctor if you have kidney disease.
Liver problems can affect how this medication works. Consult your doctor if you have liver disease.
Manufacturer's prescribing information.
National Institutes of Health (NIH): https://www.nih.gov/
American Diabetes Association (ADA): https://www.diabetes.org/
