Phenobarbitone

A barbiturate, acting as a central nervous system depressant.

Phenytoin

An anticonvulsant, primarily used to treat seizures.

Treatment of tonicclonic seizures (grand mal seizures)

Management of certain types of partial seizures

Status epilepticus (prolonged seizure activity)

May be used in combination therapy for other seizure types when monotherapy fails

Phenobarbitone enhances the inhibitory effects of GABA (gamma-aminobutyric acid) in the brain, reducing neuronal excitability. Phenytoin stabilizes neuronal membranes, reducing the spread of electrical impulses that trigger seizures.

Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children. Discard according to your pharmacist's or doctor's instructions.

Dosage is strictly individualized based on patient factors, seizure type, and response.

Always follow the prescription instructions carefully.

Never abruptly stop taking this medication without consulting a doctor.

This medication is typically taken orally.

The frequency and timing of doses vary based on individual needs.

Drowsiness

Dizziness

Unsteadiness

Fatigue

Nystagmus (involuntary eye movements)

Ataxia (lack of coordination)

Cognitive impairment

Skin rashes

Liver enzyme elevation

Blood disorders (rare)

Alcohol Consumption

Alcohol should be avoided or severely restricted as it can enhance the sedative effects of both medications, increasing the risk of falls and other complications.



While Driving or operating Machinery

Avoid driving or operating machinery until you know how this medication affects you. Drowsiness and impaired coordination are common side effects.



Pregnant & Breastfeeding Women

Use during pregnancy and breastfeeding should be carefully considered and only under close medical supervision. The medications can cross the placenta and enter breast milk.



Children

Dosage is carefully calculated based on weight and age. Close monitoring is necessary.



Kidney

Patients with kidney impairment may require dose adjustments to prevent medication accumulation.



Liver

Patients with liver impairment may require dose adjustments to prevent medication accumulation and adverse reactions.

Refer to your physician or pharmacist for specific references.

Consult the package insert provided with the medication.