Ganciclovir

Is the active ingredient in various formulations (e.g., tablets, intravenous solutions, ophthalmic gel).

Treatment of cytomegalovirus (CMV) retinitis in patients with AIDS.

Prophylaxis of CMV disease in immunocompromised individuals (e.g., organ transplant recipients).

Treatment of CMV pneumonia in immunocompromised individuals.

Gancigel Ophthalmic Gel 5gm (Ganciclovir) is a nucleoside analog that inhibits viral DNA synthesis by competitively inhibiting viral DNA polymerase. It's incorporated into viral DNA, terminating further chain elongation.

Store ganciclovir at room temperature, protected from light and moisture. Discard any unused portion according to instructions.

Dosage and administration vary significantly depending on the indication, formulation, and patient's health status. Always follow the instructions provided by your doctor or pharmacist.

Intravenous administration is common for severe infections. Oral forms are available for certain conditions.

Ophthalmic gel is used topically for CMV retinitis.

Neutropenia (low white blood cell count)

Thrombocytopenia (low platelet count)

Anemia

Nausea

Vomiting

Diarrhea

Headache

Fatigue

Fever

Rash

Kidney problems (nephrotoxicity)

Alcohol Consumption

Alcohol consumption may increase the risk of side effects. Discuss with your doctor.



While Driving or operating Machinery

Ganciclovir may cause fatigue or dizziness. Avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Ganciclovir can harm a developing fetus. It's generally avoided during pregnancy and breastfeeding. Discuss risks and benefits with your doctor.



Children

Use in children is usually only considered when the benefits outweigh the risks and is closely monitored.



Kidney

Ganciclovir can cause kidney problems. Kidney function should be monitored regularly.



Liver

Ganciclovir may affect liver function. Liver function tests should be considered.

Refer to your physician or pharmacist for complete prescribing information and package inserts.

Consult reputable medical websites and databases (e.g., FDA, medical journals).