Furosemide

A potent loop diuretic that increases urine output by blocking sodium and chloride reabsorption in the loop of henle.

Spironolactone

A potassium-sparing diuretic that blocks the action of aldosterone, a hormone that promotes sodium and water retention and potassium excretion.

Treatment of edema (fluid retention) associated with congestive heart failure, liver cirrhosis, and kidney disease.

Management of hypertension (high blood pressure), often in combination with other antihypertensive medications.

Furosemide promotes rapid diuresis by inhibiting sodium and chloride reabsorption in the loop of Henle. Spironolactone, a potassium-sparing diuretic, antagonizes the effects of aldosterone, reducing sodium and water reabsorption while conserving potassium. The combination enhances diuretic effect while minimizing potassium loss compared to using furosemide alone.

Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.

Dosage is determined by the physician based on individual needs and response. It is crucial to follow the prescribed dosage regimen precisely.

The combination of furosemide and spironolactone is usually administered orally.

Electrolyte imbalances (hypokalemia, hyponatremia, hypochloremia)

Dehydration

Dizziness

Lightheadedness

Muscle weakness or cramps

Increased thirst

Frequent urination

Gastrointestinal upset (nausea, vomiting, diarrhea)

Hyperuricemia (increased uric acid levels)

Rash

Hypotension (low blood pressure)

Alcohol Consumption

Alcohol can exacerbate dehydration and hypotension. Avoid alcohol while taking this medication.



While Driving or operating Machinery

Dizziness and lightheadedness are possible side effects. Avoid driving or operating machinery until you know how this medication affects you.



Pregnant & Breastfeeding Women

Use during pregnancy and breastfeeding is generally discouraged unless the benefits outweigh the potential risks. Consult your doctor.



Children

Use in children is generally not recommended unless specifically prescribed by a physician.



Kidney

Caution is advised in patients with impaired kidney function; dosage adjustments may be necessary.



Liver

Caution is advised in patients with impaired liver function; dosage adjustments may be necessary.

Consult your physician or pharmacist for complete prescribing information.

Refer to the medication's package insert for detailed instructions.