Flupenthixol

Nortriptyline

Treatment of depression, especially those with anxiety and agitation

Treatment of chronic schizophrenia

Flupenthixol is an antipsychotic medication that works by blocking dopamine receptors in the brain. Nortriptyline is a tricyclic antidepressant that increases levels of serotonin and norepinephrine in the brain.

Store at room temperature, protected from light and moisture. Keep out of reach of children.

Dosage is individualized and should be determined by your doctor.

This medication is typically taken once daily, usually at bedtime.

It is important to take this medication exactly as prescribed by your doctor.

Drowsiness

Dry mouth

Blurred vision

Constipation

Weight gain

Sexual dysfunction

Increased risk of seizures

Anticholinergic effects (e.g., urinary retention, constipation, dry mouth)

Cardiovascular effects (e.g., orthostatic hypotension, tachycardia)

Extrapyramidal symptoms (e.g., tremors, muscle rigidity, akathisia)

Neuroleptic malignant syndrome (rare but serious)

Serotonin syndrome (rare but serious)

Alcohol Consumption

Avoid alcohol while taking this medication as it can increase the risk of side effects.



While Driving or Operating Machinery

This medication can cause drowsiness. Avoid driving or operating machinery until you know how it affects you.



Pregnant & Breastfeeding Women

This medication is not recommended for pregnant or breastfeeding women. Talk to your doctor about the risks and benefits.



Children

This medication is not typically prescribed for children.



Kidney

This medication may need to be adjusted in people with kidney problems.



Liver

This medication may need to be adjusted in people with liver problems.

The prescribing information for Flupenthixol + Nortriptyline

The National Library of Medicine's MedlinePlus website

The National Institute of Mental Health website