Methotrexate

Methotrexate is the primary active ingredient.Specific formulations may contain inactive ingredients like preservatives, stabilizers, and fillers. Always check the medication label for a complete list.

Rheumatoid arthritis

Psoriatic arthritis

Juvenile idiopathic arthritis

Certain types of cancer (e.g., choriocarcinoma, lymphoma, leukemia)

Severe psoriasis

Ectopic pregnancy (under specific medical supervision)

Folitrax 7.5 Inj (Methotrexate) inhibits dihydrofolate reductase, an enzyme crucial for DNA synthesis. By blocking this enzyme, it slows down the rapid cell division characteristic of cancerous cells and inflammatory processes in autoimmune diseases.

Store methotrexate at room temperature, away from moisture and direct sunlight. Dispose of unused medication properly according to your pharmacist's or healthcare provider's instructions.

Dosage is highly individualized and determined by your physician based on your condition, weight, and response to treatment.

It can be administered orally, intramuscularly, intravenously, or intrathecally (directly into the spinal fluid) depending on the indication.

Never adjust your dosage without consulting your doctor.

Nausea

Vomiting

Diarrhea

Mouth sores

Hair loss

Fatigue

Liver damage

Kidney damage

Increased risk of infections

Pneumonitis (lung inflammation)

Alcohol Consumption

Avoid excessive alcohol consumption as it can increase the risk of liver damage.



While Driving or operating Machinery

Methotrexate can cause fatigue and drowsiness; avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Methotrexate is highly teratogenic (causes birth defects). It should not be used during pregnancy or breastfeeding unless strictly necessary under strict medical supervision. Effective contraception is mandatory.



Children

Dosage and administration in children are determined by the physician based on weight and condition.



Kidney

Kidney function should be monitored regularly, especially in patients with pre-existing kidney disease. Dosage adjustment might be needed.



Liver

Liver function tests are crucial before starting and during treatment. Methotrexate can cause liver damage; alcohol should be avoided.

Consult your physician or pharmacist for complete and updated information.

Refer to the official prescribing information (package insert) provided by the drug manufacturer.