Prescription Required.Why?
Methotrexate (the active ingredient)Inactive ingredients (vary depending on formulation – check product packaging)
Rheumatoid arthritis
Psoriatic arthritis
Juvenile idiopathic arthritis
Ankylosing spondylitis
Certain types of cancer (e.g., leukemia, lymphoma)
Severe psoriasis
Ectopic pregnancy (in specific circumstances under medical supervision)
Folitrax 25 Inj (Methotrexate) inhibits dihydrofolate reductase, an enzyme essential for DNA synthesis. This interferes with cell division and growth, slowing the progression of inflammatory diseases and cancerous cells.
Store at room temperature, away from direct sunlight and moisture. Keep out of reach of children. Do not use if the medication is expired or shows signs of deterioration.
Dosage varies greatly depending on the condition being treated and the patient's individual needs.
It may be administered orally, intravenously, or intramuscularly.
Dosage should be determined and monitored closely by a healthcare professional.
Never adjust the dose yourself without consulting your doctor.
Nausea
Vomiting
Diarrhea
Mouth sores
Hair loss
Fatigue
Liver damage
Kidney damage
Bone marrow suppression
Infections
Pneumonitis
Severe allergic reactions
Alcohol consumption should be minimized or avoided entirely while taking methotrexate, as it can increase the risk of liver damage.
Methotrexate can cause fatigue and other side effects that may impair judgment or coordination. Avoid driving or operating machinery if affected.
Methotrexate is teratogenic (causes birth defects) and should not be used during pregnancy or breastfeeding unless strictly necessary and under close medical supervision. Reliable contraception is crucial.
Use in children is only appropriate under strict medical supervision due to potential developmental side effects.
Methotrexate can impair kidney function. Kidney function should be monitored regularly during treatment.
Methotrexate can cause liver damage; liver function should be monitored regularly, and alcohol should be avoided.
Your doctor or pharmacist
The medication's package insert
Reputable medical websites (e.g., Mayo Clinic, NHS)
