Clindamycin

An antibiotic that fights bacterial infections by preventing bacteria from producing essential proteins.

Niacinamide

A form of vitamin b3 with potential anti-inflammatory and skin-barrier-improving properties. its role in combination with clindamycin is primarily to improve skin tolerability and potentially enhance the efficacy of clindamycin in acne treatment.

Treatment of acne vulgaris (moderate to severe inflammatory acne)

May be used in combination to address both the infection and inflammation associated with acne.

Clindamycin inhibits bacterial protein synthesis, leading to bacterial cell death. Niacinamide's mechanism in this combination is not fully elucidated but likely involves reducing inflammation and improving the skin barrier function, potentially improving clindamycin's efficacy and reducing irritation.

Store at room temperature, away from direct sunlight and moisture. Keep out of reach of children.

Dosage should be determined by a physician based on the individual's condition and response to treatment.

Typically applied topically to affected skin areas as directed by a healthcare professional.

Do not exceed the recommended dose.

Skin irritation (redness, burning, itching, dryness)

Increased sensitivity to sunlight

Allergic reactions (rash, hives, swelling)

Gastrointestinal upset (if ingested accidentally)

Alcohol Consumption

No specific interaction with alcohol is known, but excessive alcohol consumption may generally worsen skin conditions.



While Driving or operating Machinery

Generally considered safe, but potential side effects like drowsiness (though rare with topical application) should be considered.



Pregnant & Breastfeeding Women

Consult your physician before using this medication during pregnancy or breastfeeding.



Children

Use in children should be determined by a physician.



Kidney

Generally well-tolerated, but caution is advised in individuals with severe kidney impairment.



Liver

Generally well-tolerated, but caution is advised in individuals with severe liver impairment.

Consult your physician or pharmacist for detailed information and specific references related to the formulation you are using.

Reputable medical websites (e.g., Mayo Clinic, NIH) can provide general information on acne and its treatments.