Cyclophosphamide

Cyclophosphamide is the active ingredient in this medication.It belongs to a class of drugs called alkylating agents.It comes in various formulations, including oral tablets, intravenous solution, and powder for injection.The specific formulation and ingredients may vary depending on the manufacturer and intended use.

Cancer treatment: Leukemia, lymphoma, multiple myeloma, breast cancer, ovarian cancer, lung cancer, and others.

Autoimmune diseases: Rheumatoid arthritis, lupus, vasculitis, and inflammatory bowel disease.

Organ transplantation: To prevent rejection of a transplanted organ.

Nephrotic syndrome: A rare kidney disorder.

Endoxan N 500mg Inj (Cyclophosphamide) works by interfering with the growth and division of cancer cells and immune system cells. It achieves this by damaging the DNA within these cells, preventing their replication and ultimately leading to their destruction.

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Store at room temperature, away from moisture and heat.

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Keep the medication in its original container.

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Protect from light.

3

Do not use the medication after the expiration date.

4

Dispose of expired or unused medication as instructed by your healthcare professional.

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Keep out of reach of children and pets.

The dosage of cyclophosphamide will be determined by your doctor based on your individual condition, age, weight, and other factors.

It is typically taken orally, administered intravenously, or injected intramuscularly.

Follow your doctor's instructions carefully and do not alter the dosage or frequency without their guidance.

Low blood cell counts (including anemia, neutropenia, and thrombocytopenia)

Nausea and vomiting

Hair loss

Infertility

Increased risk of infections

Kidney problems

Liver problems

Heart problems

Lung problems

Second cancers

Severe allergic reactions

Alcohol Consumption

Avoid alcohol while taking cyclophosphamide, as it can increase the risk of side effects, particularly liver damage.



While Driving or Operating Machinery

Be cautious while driving or operating machinery, as cyclophosphamide can cause drowsiness, dizziness, and other side effects that may impair your ability to perform these activities.



Pregnant & Breastfeeding Women

Cyclophosphamide is known to be harmful to a developing fetus and should not be used during pregnancy.



Children

Use in children is only recommended in specific circumstances and under close medical supervision.



Kidney

Cyclophosphamide can affect kidney function, so patients with kidney problems should be monitored closely.



Liver

Cyclophosphamide can affect liver function, so patients with liver problems should be monitored closely.

National Cancer Institute: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/cyclophosphamide

Drugs.com: https://www.drugs.com/cyclophosphamide.html

Mayo Clinic: https://www.mayoclinic.org/diseases-conditions/rheumatoid-arthritis/diagnosis-treatment/drc-20353642