Megestrol Acetate

Is the active ingredient.

Treatment of anorexia and cachexia associated with AIDS.

Treatment of anorexia and weight loss in patients with cancer.

Endace 160mg Tab (Megestrol Acetate) is a synthetic progestin that binds to progesterone receptors. Its mechanism in stimulating appetite and weight gain is not fully understood but may involve effects on the central nervous system and metabolic processes.

Store at room temperature (20°C to 25°C), protect from light and moisture. Keep out of reach of children.

Dosage and administration should always be determined by a physician and tailored to the individual patient's needs and response.

Oral administration is typical.

Doses may vary significantly depending on the indication and patient factors.

Increased appetite and weight gain.

Fluid retention (edema).

Thromboembolic events (blood clots).

Glucose intolerance or hyperglycemia.

Mood changes.

Fatigue.

Nausea and vomiting.

Diarrhea or constipation.

Breast tenderness.

Alcohol Consumption

The interaction between megestrol acetate and alcohol is not well-established, but excessive alcohol consumption is generally advised against.



While Driving or operating Machinery

Drowsiness or dizziness can occur; avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Should not be used during pregnancy or breastfeeding. It can harm the fetus.



Children

Safety and efficacy in children have not been established.



Kidney

Renal impairment may require dosage adjustment; consult a physician.



Liver

Hepatic impairment may require dosage adjustment; consult a physician.

Consult your physician or pharmacist for detailed information and references.