Edaravone

Is the active ingredient in the medication.

Edaravone is currently approved by the FDA for the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

It may be used to slow the progression of ALS but does not cure the disease.

It's important to note that edaravone is not a treatment for other neurological conditions.

0 Edinova 1.5mg Inj (Edaravone) is an antioxidant that works by scavenging free radicals, which are unstable molecules that can damage cells.1 In ALS, free radicals contribute to the degeneration of motor neurons, the nerve cells responsible for muscle movement.2 By reducing oxidative stress, edaravone may help slow the progression of the disease.3 However, the exact mechanism by which edaravone works in ALS is not fully understood.

0

Edaravone should be stored at room temperature, between 68°F and 77°F (20°C and 25°C).

1

Protect it from light and moisture.

2

Keep it out of reach of children and pets.

The usual starting dose of edaravone is 60 mg given intravenously over 60 minutes once a day.

The medication is typically administered in a clinic or hospital setting.

Dosage and frequency may be adjusted based on individual patient needs and response.

Common side effects include:

Serious side effects are less common but can occur.

Nausea

Vomiting

Headache

Dizziness

Rash

Infusion-related reactions (e.g., flushing, chills, fever)

Injection site reactions (e.g., pain, redness, swelling)

Alcohol Consumption

It is generally recommended to avoid excessive alcohol consumption while taking edaravone.



While Driving or operating Machinery

Edaravone may cause dizziness or drowsiness. Do not drive or operate machinery until you know how this medication affects you.



Pregnant & Breastfeeding Women

It is not known if edaravone is safe for use during pregnancy or breastfeeding. Consult with your doctor if you are pregnant or breastfeeding before taking this medication.



Children

Edaravone is not approved for use in children. It is not recommended for children.



Kidney

Edaravone may be cleared from the body through the kidneys. Patients with kidney disease may require dose adjustments.



Liver

Edaravone may be cleared from the body through the liver. Patients with liver disease may require dose adjustments.

U.S. Food and Drug Administration (FDA): https://www.fda.gov/

National Institutes of Health (NIH): https://www.nih.gov/

Amyotrophic Lateral Sclerosis Association (ALSA): https://www.alsa.org/

Drug manufacturer's website: (Consult the website of the specific company that manufactures the medication you are taking.)