Duloxetine

A serotonin-norepinephrine reuptake inhibitor (snri) antidepressant.

Methylcobalamin

A form of vitamin b12, essential for nerve function and the production of red blood cells.

Treatment of major depressive disorder (MDD)

Management of generalized anxiety disorder (GAD)

Relief of chronic musculoskeletal pain, such as fibromyalgia and diabetic peripheral neuropathy

Management of neuropathic pain

0 Duloxetine: Increases levels of serotonin and norepinephrine in the brain, which are neurotransmitters involved in mood regulation and pain perception.1 Methylcobalamin: Plays a vital role in nerve health and function by acting as a coenzyme in various metabolic processes.

0

Store at room temperature, protected from light and moisture.

1

Keep out of reach of children.

2

Do not use after the expiration date printed on the label.

The dosage of duloxetine + methylcobalamin will vary depending on the individual's condition, age, and response to treatment.

It is crucial to follow your doctor's prescribed dosage and instructions carefully.

Typically taken orally once daily, with or without food.

Increased risk of bleeding, especially in individuals with a history of bleeding disorders

Nausea

Dizziness

Headache

Dry mouth

Constipation

Fatigue

Insomnia

Increased sweating

Sexual dysfunction

Alcohol Consumption

Alcohol may increase the risk of side effects, including drowsiness and dizziness. Avoid alcohol consumption while taking this medication.



While Driving or operating Machinery

This medication may cause drowsiness, dizziness, and impaired concentration. Avoid driving or operating machinery until you know how this medication affects you.



Pregnant & Breastfeeding Women

Consult your doctor before taking this medication if you are pregnant or breastfeeding. It is unclear whether this medication passes into breast milk and could harm a nursing infant.



Children

The safety and effectiveness of duloxetine + methylcobalamin in children have not been established. It should not be used in children.



Kidney

Caution is advised in individuals with kidney disease. Your doctor may need to adjust your dosage.



Liver

Caution is advised in individuals with liver disease. Your doctor may need to adjust your dosage.

National Institutes of Health (NIH)

Food and Drug Administration (FDA)

The American Psychiatric Association (APA)