Duloxetine

A serotonin-norepinephrine reuptake inhibitor (snri) antidepressant.

Methylcobalamin

A form of vitamin b12, essential for nerve function and red blood cell production.

Treatment of major depressive disorder (MDD)

Management of generalized anxiety disorder (GAD)

Relief of neuropathic pain, such as diabetic neuropathy

Treatment of fibromyalgia

Duloxetine increases levels of serotonin and norepinephrine in the brain, which are neurotransmitters involved in mood regulation and pain perception. Methylcobalamin supports nerve health and function, which can contribute to the overall effectiveness of the medication.

Store the medication in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets.

The dosage and frequency of administration will vary depending on the individual patient's condition and response to treatment.

It is typically taken orally, with or without food.

It's crucial to follow the prescribed dosage and instructions carefully.

Nausea

Dizziness

Headache

Dry mouth

Constipation

Loss of appetite

Sleep disturbances

Increased sweating

Sexual dysfunction

Alcohol Consumption

Alcohol may increase the risk of side effects, including dizziness and drowsiness. It's best to avoid or limit alcohol consumption while taking this medication.



While Driving or Operating Machinery

This medication can cause drowsiness, dizziness, and impaired concentration. It's important to avoid driving or operating machinery until you know how this medication affects you.



Pregnant & Breastfeeding Women

Duloxetine may pose risks to a developing fetus. It's important to discuss the risks and benefits with your doctor if you are pregnant or planning to become pregnant. It is also not recommended for breastfeeding mothers.



Children

This medication is not typically prescribed for children.



Kidney

This medication should be used with caution in patients with kidney problems, as it can be cleared through the kidneys. Your doctor may adjust your dosage.



Liver

This medication should be used with caution in patients with liver problems, as it can be metabolized by the liver. Your doctor may adjust your dosage.

https://www.drugs.com/duloxetine.html

https://www.mayoclinic.org/diseases-conditions/depression/symptoms-causes/syc-20356007

https://www.ncbi.nlm.nih.gov/pubmed/23400946

https://www.healthline.com/health/duloxetine-side-effects