Repaglinide: A medication that belongs to the meglitinide class of drugs. It helps to stimulate the pancreas to produce more insulin.

Metformin: A medication belonging to the biguanide class. It helps improve insulin sensitivity and decrease glucose production by the liver.

Type 2 diabetes mellitus (adult onset diabetes) when diet and exercise alone are not sufficient to control blood sugar levels.

May be used in combination with other diabetes medications like sulfonylureas or insulin.

Repaglinide and Metformin work together to lower blood sugar levels. Repaglinide stimulates the pancreas to release more insulin, particularly in response to a meal. Metformin improves insulin sensitivity in tissues and reduces glucose production by the liver. This combined action helps control blood sugar levels throughout the day.

Store the medication at room temperature, away from moisture and direct sunlight. Keep it out of reach of children and pets.

The dosage of Repaglinide and Metformin is tailored to each individual patient and will be determined by your healthcare provider based on factors like your blood sugar levels, overall health, and other medications you are taking.

The medication is typically taken orally before meals. The specific timing and frequency of doses will be provided by your doctor.

Do not crush, chew, or break the tablets. Swallow them whole with a glass of water.

It is important to follow your doctor's instructions carefully and not change your dosage without consulting them.

Common side effects include nausea, vomiting, diarrhea, abdominal pain, and low blood sugar (hypoglycemia).

Serious side effects may include lactic acidosis (a buildup of lactic acid in the blood), vitamin B12 deficiency, and liver problems.

Less common side effects include weight loss, headache, dizziness, rash, and joint pain.

Alcohol Consumption

Alcohol can increase the risk of low blood sugar (hypoglycemia). It is important to limit alcohol intake while taking this medication and talk to your doctor about safe consumption levels.



While Driving or Operating Machinery

This medication can cause dizziness and low blood sugar, which can impair your ability to drive or operate machinery safely. Avoid these activities if you feel dizzy or experience low blood sugar.



Pregnant & Breastfeeding Women

Repaglinide and Metformin may not be safe for pregnant or breastfeeding women. Consult your doctor before taking this medication if you are pregnant or breastfeeding.



Children

This medication is not recommended for children.



Kidney

Patients with kidney problems may require dose adjustments or may not be able to take this medication safely. Consult your doctor before taking this medication if you have kidney problems.



Liver

Patients with liver problems may require dose adjustments or may not be able to take this medication safely. Consult your doctor before taking this medication if you have liver problems.

The United States Pharmacopeia (USP)

The National Institutes of Health (NIH)

The Food and Drug Administration (FDA)