Disulfiram

Disulfiram (generic name)Antabuse (brand name)

Treatment of chronic alcoholism

Used in conjunction with behavioral therapy and counseling

Helps prevent relapse by causing unpleasant reactions when alcohol is consumed

Disulfiram 250mg Tab (Disulfiram) blocks the enzyme aldehyde dehydrogenase, which is essential for metabolizing alcohol. When alcohol is consumed, it builds up in the body, causing severe side effects like flushing, nausea, vomiting, headache, and dizziness. This unpleasant reaction discourages further alcohol consumption.

Store at room temperature, away from heat and moisture. Keep out of reach of children and pets.

Dosage varies depending on the individual's needs and response to treatment.

Typically taken once daily, usually in the morning.

It is important to follow your doctor's instructions carefully.

Swallow tablets whole with a full glass of water.

Nausea, vomiting

Headache

Drowsiness

Fatigue

Metallic taste in mouth

Skin rash

Hepatitis (liver inflammation)

Neurological effects like peripheral neuropathy

Alcohol Consumption

Absolutely avoid alcohol during disulfiram treatment. Even small amounts can trigger severe reactions.



While Driving or Operating Machinery

Disulfiram can cause drowsiness and dizziness. Avoid driving or operating machinery until you know how it affects you.



Pregnant & Breastfeeding Women

Disulfiram is not recommended for pregnant or breastfeeding women. It can harm the fetus or pass into breast milk.



Children

Disulfiram is not approved for use in children.



Kidney

Disulfiram may need to be adjusted in individuals with kidney problems.



Liver

Disulfiram can cause liver damage. It is essential to monitor liver function regularly during treatment.

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Food and Drug Administration (FDA)

MedlinePlus (National Institutes of Health)