Darbepoetin Alfa

Is the active ingredient. it is a form of erythropoietin, a hormone that stimulates red blood cell production.

Treatment of anemia associated with chronic kidney disease (CKD)

Treatment of anemia in patients with nonmyeloid malignancies receiving chemotherapy

Treatment of anemia in patients undergoing surgery and other medical conditions associated with blood loss

Dargen 25mcg Inj (Darbepoetin Alfa) acts by binding to erythropoietin receptors on erythroid progenitor cells in the bone marrow. This binding stimulates the production and maturation of red blood cells, increasing hemoglobin levels and improving oxygen-carrying capacity of the blood.

Store at 2°C to 8°C (36°F to 46°F). Protect from light. Do not freeze. Discard any unused portion after the expiration date.

Dosage is determined by the physician based on individual needs and response. It is typically administered subcutaneously (under the skin).

The initial dose and subsequent dose adjustments are based on hemoglobin levels, hematocrit, and response to therapy.

Do not administer intravenously.

Redness or pain at the injection site

Hypertension (high blood pressure)

Headache

Nausea

Vomiting

Fatigue

Thromboembolic events (blood clots)

Alcohol Consumption

The effect of alcohol consumption on darbepoetin alfa is not well established. Patients should consult their physician.



While Driving or operating Machinery

Patients experiencing side effects such as dizziness or fatigue should avoid driving or operating machinery.



Pregnant & Breastfeeding Women

Use during pregnancy and breastfeeding should only be considered if the potential benefits outweigh the potential risks. Consult your physician.



Children

Safety and efficacy in children have not been fully established. Use should be based on individual physician assessment.



Kidney

Darbepoetin alfa is used to treat anemia related to kidney disease, but careful monitoring is crucial. Dose adjustments may be necessary.



Liver

Patients with severe liver impairment require careful monitoring. Dose adjustments may be necessary.

Please consult your physician or refer to the official drug prescribing information for the most accurate and up-to-date details.