Ketoconazole is an antifungal medication that works by stopping the growth of fungus.

Coal tar is a thick, black liquid produced by the destructive distillation of coal. It has anti-inflammatory and anti-proliferative properties and is used to treat skin conditions like psoriasis.

This drug combination is typically prescribed for the treatment of severe, recalcitrant psoriasis when other treatments have not been effective.

It may be used to treat seborrheic dermatitis as well.

Ketoconazole inhibits the growth of fungus by interfering with the synthesis of ergosterol, a vital component of fungal cell membranes. Coal tar acts as an anti-inflammatory and anti-proliferative agent, reducing inflammation and the rapid growth of skin cells characteristic of psoriasis.

Store the medication in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets.

The dosage and administration of ketoconazole + coal tar will be determined by your doctor based on your specific condition and medical history.

It is typically applied to the affected area of skin once or twice daily, as directed by your doctor.

Avoid contact with eyes, mouth, and mucous membranes. Wash your hands thoroughly after applying the medication.

Skin irritation, redness, itching, dryness

Burning sensation

Allergic reactions (rash, hives, swelling)

Hair discoloration

Increased sensitivity to sunlight

Liver problems (rare)

Alcohol Consumption

Avoid excessive alcohol consumption while using this medication. Alcohol can increase the risk of liver damage.



While Driving or Operating Machinery

This medication is unlikely to affect your ability to drive or operate machinery, but it's important to be aware of any potential side effects that could affect your concentration or coordination.



Pregnant & Breastfeeding Women

This medication is not recommended for use during pregnancy or breastfeeding. Consult your doctor for advice on alternative treatments.



Children

This medication is not typically prescribed for children. Consult your doctor for specific advice.



Kidney

This medication may be used with caution in individuals with kidney problems. Your doctor will monitor your kidney function.



Liver

This medication may increase the risk of liver damage. It is important to monitor liver function regularly, especially if you have any pre-existing liver conditions or are taking other medications that can affect the liver.

National Psoriasis Foundation: https://www.psoriasis.org/

American Academy of Dermatology: https://www.aad.org/