Isotretinoin

Is the active ingredient.

Severe recalcitrant nodular acne unresponsive to other treatments.

Severe cystic acne.

Dacne I 10mg Cap (Isotretinoin) reduces sebum production, inhibits keratinization (the process of skin cell maturation), and possesses anti-inflammatory properties, thus effectively treating acne vulgaris.

Store at controlled room temperature, 20°C to 25°C (68°F to 77°F). Protect from light and moisture. Keep out of reach of children.

Dosage is determined by a physician based on individual needs and tolerance.

Typically administered orally, once or twice daily with food.

Treatment duration is usually several months and varies depending on the patient's response.

Dry skin, lips, and mucous membranes

Nosebleeds

Increased sensitivity to sunlight

Muscle aches

Joint pain

Elevated cholesterol and triglycerides

Headache

Inflammation of the eyes (conjunctivitis)

Alcohol Consumption

Alcohol consumption may exacerbate side effects, especially dryness. Moderation or avoidance is recommended.



While Driving or operating Machinery

Drowsiness and visual disturbances can occur; avoid driving or operating machinery if affected.



Pregnant & Breastfeeding Women

Isotretinoin is highly teratogenic (causes birth defects). It is absolutely contraindicated in pregnancy and breastfeeding women. Strict contraception is mandatory.



Children

Use in children is generally not recommended except in severe cases and under strict medical supervision.



Kidney

Renal impairment may affect drug metabolism. Dosage adjustments may be needed.



Liver

Hepatic impairment may affect drug metabolism. Regular liver function tests are necessary.

Your physician or pharmacist

Package insert of the specific brand of isotretinoin being used

Reputable medical websites such as the National Institutes of Health (NIH) or the Mayo Clinic