Cyclophosphamide

Cyclophosphamide (active ingredient)Inactive ingredients (vary depending on formulation – check product label)

Treatment of various cancers, including leukemias, lymphomas, multiple myeloma, and some solid tumors

Treatment of autoimmune diseases like lupus nephritis and rheumatoid arthritis (in specific cases and under close medical supervision)

Used in immunosuppressive regimens for organ transplantation (under strict medical guidance)

Cycloxan 50mg Tab (Cyclophosphamide) is an alkylating agent. It works by damaging the DNA of rapidly dividing cells, including cancer cells and some immune cells. This interferes with their ability to reproduce and grow.

Store at room temperature, away from direct sunlight and moisture. Keep out of reach of children. Discard any unused medication according to your pharmacist's instructions.

Dosage is highly individualized and determined by your doctor based on your specific condition, age, weight, and overall health.

It's commonly administered intravenously (IV) or orally (as tablets or capsules).

Never change your dosage or stop taking the medication without consulting your doctor.

Increased risk of infections (due to immunosuppression)

Bone marrow suppression (leading to anemia, leukopenia, and thrombocytopenia)

Nausea and vomiting

Hair loss (alopecia)

Mouth sores (mucositis)

Fatigue

Bladder problems (including hemorrhagic cystitis)

Infertility (potential longterm effect)

Alcohol Consumption

Alcohol consumption should be discussed with your doctor. It may exacerbate some side effects.



While Driving or operating Machinery

Avoid driving or operating machinery if experiencing side effects like fatigue or dizziness.



Pregnant & Breastfeeding Women

Cyclophosphamide is contraindicated in pregnancy due to its teratogenic effects. It is not recommended for breastfeeding women.



Children

Dosage and monitoring are carefully adjusted for children.



Kidney

Kidney function should be monitored closely as cyclophosphamide is primarily excreted by the kidneys. Dosage adjustments may be necessary in patients with impaired renal function.



Liver

Liver function should be monitored as cyclophosphamide can affect liver function. Dosage adjustments might be needed for patients with liver disease.

Consult your doctor or pharmacist for comprehensive information and references.

Refer to the package insert for detailed product information.

PubMed and other reputable medical databases.