Metformin

A biguanide that improves insulin sensitivity and reduces glucose production by the liver.

Type 2 diabetes mellitus, especially when diet and exercise alone are insufficient to control blood glucose levels.

Used in patients requiring a combination therapy to achieve optimal glycemic control.

This triple combination medication works synergistically to manage blood sugar. Voglibose slows carbohydrate digestion, Metformin improves insulin sensitivity and reduces hepatic glucose production, and Gliclazide stimulates insulin release from the pancreas. This combined action helps to lower blood glucose levels more effectively than any single agent alone.

Store in a cool, dry place, protected from light and moisture. Keep out of reach of children. Discard any medication past its expiry date.

Dosage should be determined by a physician based on individual needs and response to therapy. It's crucial to follow the prescribed dosage regimen strictly.

Usually started at lower doses and gradually increased as tolerated. This is to minimize the risk of side effects and allow the body to adapt.

Medication is typically taken with meals.

Gastrointestinal disturbances (nausea, vomiting, diarrhea, abdominal pain)

Hypoglycemia (low blood sugar)

Weight gain

Allergic reactions (rash, itching, swelling)

Headache

Fatigue

Alcohol Consumption

Alcohol consumption can increase the risk of hypoglycemia and lactic acidosis. Patients should limit alcohol intake or avoid it altogether while taking this medication.



Driving or operating Machinery

Hypoglycemia can impair judgment and coordination. Patients should avoid driving or operating machinery if they experience symptoms of low blood sugar.



Pregnant & Breastfeeding Women

Generally not recommended during pregnancy and breastfeeding. Consult a physician immediately.



Children

Not recommended for children.



Kidney

Use with caution in patients with kidney disease. Dose adjustments may be necessary.



Liver

Use with caution in patients with liver disease. Dose adjustments may be necessary.

Refer to your doctor or pharmacist for detailed information and specific instructions related to this medicine.

Consult the patient information leaflet provided with the medication.

Relevant medical textbooks and clinical guidelines on diabetes management.