Mifepristone

Misoprostol

Medical abortion (termination of early pregnancy)

Treatment of heavy menstrual bleeding

Mifepristone is a progesterone antagonist, blocking the action of progesterone, a hormone essential for pregnancy maintenance. Misoprostol is a prostaglandin analog, which softens the cervix and causes uterine contractions, leading to expulsion of the pregnancy. The combination of these drugs effectively terminates a pregnancy.

Store mifepristone and misoprostol at room temperature, protected from light and moisture. Keep out of reach of children.

Dosage and administration will vary depending on the indication and individual patient factors. It is crucial to follow the doctor's instructions precisely.

Mifepristone is usually taken orally, while misoprostol can be taken orally or vaginally.

Bleeding (heavy or prolonged), cramping, nausea, vomiting, diarrhea, headache, fever, dizziness

Alcohol Consumption

Avoid alcohol consumption during treatment as it can increase the risk of side effects.



While Driving or operating Machinery

Avoid driving or operating machinery if you experience dizziness or other side effects that may impair your alertness.



Pregnant & Breastfeeding Women

This medication is not intended for use during pregnancy. Consult your doctor before using this medication if you are breastfeeding.



Children

This medication is not intended for use in children.



Kidney

Caution is advised in individuals with kidney problems. Your doctor may adjust the dosage or monitor you more closely.



Liver

Caution is advised in individuals with liver problems. Your doctor may adjust the dosage or monitor you more closely.

Food and Drug Administration (FDA)

World Health Organization (WHO)

Gynuity Health Projects

American College of Obstetricians and Gynecologists (ACOG)