Penicillamine

Penicillamine is the active ingredient in medications containing this drug.It is a derivative of penicillin, but it does not have antibiotic properties.

Treatment of Wilson's disease (a rare genetic disorder that causes copper to accumulate in the body)

Treatment of rheumatoid arthritis (an autoimmune disease that causes inflammation of the joints)

Treatment of cystinuria (a genetic disorder that causes kidney stones)

Treatment of heavy metal poisoning (such as mercury or lead poisoning)

Cilamin 250mg Cap (Penicillamine) works by binding to copper, mercury, and other heavy metals in the body, forming complexes that are then excreted in the urine. This helps to remove excess copper from the body in patients with Wilson's disease and to reduce the levels of heavy metals in the body in cases of poisoning. In rheumatoid arthritis, penicillamine's exact mechanism of action is not fully understood, but it is thought to suppress the immune system and reduce inflammation.

Penicillamine should be stored at room temperature, away from light and moisture. It is important to keep this medication out of reach of children and pets.

The dosage of penicillamine will vary depending on the condition being treated and the individual patient.

It is usually taken by mouth, with or without food.

The medication should be taken exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without talking to your doctor first.

It is important to take penicillamine on a regular schedule to get the most benefit from it.

Nausea

Vomiting

Diarrhea

Loss of appetite

Stomach pain

Headache

Dizziness

Skin rash

Itching

Fever

Joint pain

Muscle weakness

Blood abnormalities

Kidney problems

Liver problems

Alcohol Consumption

It is generally advised to avoid alcohol consumption while taking penicillamine, as it may increase the risk of side effects. Consult your doctor for specific guidance.



While Driving or operating Machinery

Penicillamine may cause dizziness or drowsiness, so it is important to be careful when driving or operating machinery. If you experience these side effects, avoid these activities.



Pregnant & Breastfeeding Women

Penicillamine can harm an unborn baby. It is not recommended for use during pregnancy. Penicillamine passes into breast milk and can harm a breastfeeding baby. It is not recommended for use while breastfeeding.



Children

Penicillamine is not typically recommended for children, unless under the guidance of a specialist and for specific conditions.



Kidney

Patients with kidney problems may need to be monitored closely while taking penicillamine. Your doctor may adjust your dosage based on your kidney function.



Liver

Patients with liver problems should use penicillamine with caution, as it can potentially worsen liver function. Close monitoring is necessary.

https://www.drugs.com/mtm/penicillamine.html

https://www.mayoclinic.org/diseases-conditions/wilsons-disease/diagnosis-treatment/drc-20354211

https://www.ncbi.nlm.nih.gov/pubmed/23462507

https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Rheumatoid-Arthritis/Treatments-for-Rheumatoid-Arthritis/Medication/Disease-Modifying-Antirheumatic-Drugs-DMARDs/Penicillamine