Dihydrochloride
Treatment of chronic stable angina pectoris (chest pain) in patients who are inadequately controlled by, or intolerant of, other antianginal treatments.
Prevention of angina attacks.
Cardimax Sr Tab (Trimetazidine) inhibits the long-chain 3-ketoacyl-CoA thiolase enzyme, an enzyme involved in fatty acid oxidation. By inhibiting this enzyme, it shifts myocardial energy metabolism from fatty acid oxidation to glucose oxidation, thus improving myocardial energy supply and reducing oxygen demand. This helps to reduce the frequency and severity of angina attacks.
Store at room temperature (20-25°C). Protect from moisture and light. Keep out of the reach of children.
Dosage should be determined by a physician.
The usual starting dose is 35 mg twice daily (morning and evening).
The dose may be increased to 70 mg twice daily if needed, but only as per doctor’s instruction.
Nausea
Vomiting
Abdominal pain
Headache
Dizziness
Fatigue
Insomnia
The interaction between trimetazidine and alcohol is not well documented, but it's advisable to limit alcohol consumption as excessive alcohol can have negative effects on heart health.
Trimetazidine can cause dizziness and fatigue. Avoid driving or operating machinery if you experience these side effects.
The use of trimetazidine during pregnancy and breastfeeding should only be considered if the potential benefits outweigh the potential risks. Consult with a doctor before using this medication during pregnancy or breastfeeding.
The safety and effectiveness of trimetazidine in children have not been established.
Renal impairment may affect the elimination of trimetazidine, requiring dose adjustment. Consult with a doctor if you have kidney problems.
There is limited information on how the liver affects the metabolism and excretion of trimetazidine. Consult with a doctor if you have liver problems.
Consult your physician or pharmacist for detailed information and references.
Please refer to the patient information leaflet provided with your medication.
