Heparin

Heparin is a naturally occurring anticoagulant, a type of medication that helps prevent blood clots from forming and growing.It is derived from porcine (pig) intestinal mucosa or bovine (cow) lung tissue.Heparin is available in various formulations, including injectable solutions, pre-filled syringes, and intravenous (IV) bags.

Prevention and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE)

Treatment of unstable angina and nonST-segment elevation myocardial infarction (NSTEMI)

Prevention of clot formation during and after surgery

Treatment of atrial fibrillation with a high risk of stroke

Treatment of disseminated intravascular coagulation (DIC)

Treatment of heparininduced thrombocytopenia (HIT) in some cases

Hep 25 (25000) Inj (Heparin) works by activating antithrombin III, a naturally occurring protein in the blood. Antithrombin III then inhibits the activity of clotting factors like thrombin and factor Xa, which are essential for blood clot formation. This process prevents the formation and growth of blood clots, reducing the risk of life-threatening conditions like stroke, heart attack, and pulmonary embolism.

Heparin should be stored at room temperature, away from direct sunlight and moisture. It should not be frozen. Discard any unused portion after the expiration date.

The dosage of heparin varies depending on the individual's condition, weight, and the specific indication for use.

Heparin is typically administered intravenously (IV) or subcutaneously (SC).

The frequency of administration can range from once daily to multiple times per day.

It is crucial to follow the doctor's instructions carefully regarding dosage and administration.

Heparin is often monitored through blood tests to ensure the correct dosage and prevent complications.

Bleeding (most common side effect)

Heparininduced thrombocytopenia (HIT)

Osteoporosis (longterm use)

Allergic reactions

Skin reactions at the injection site

Increased liver enzyme levels

Alcohol Consumption

Avoid alcohol consumption while on heparin, as it can increase the risk of bleeding.



While Driving or Operating Machinery

Heparin can cause dizziness and drowsiness in some individuals. Avoid driving or operating machinery until you know how heparin affects you.



Pregnant & Breastfeeding Women

Heparin is generally considered safe for pregnant and breastfeeding women when used under the supervision of a healthcare professional. However, it's important to discuss any concerns with your doctor.



Children

Heparin is used in children, but the dosage and administration are adjusted based on the child's age and weight.



Kidney

Heparin is primarily eliminated by the kidneys. Therefore, patients with kidney problems may require dose adjustments.



Liver

Heparin does not typically affect liver function.

U.S. National Library of Medicine, MedlinePlus: https://medlineplus.gov/druginfo/meds/a601049.html

American Heart Association: https://www.heart.org/en/health-topics/heart-attack/what-is-a-heart-attack/anticoagulants-blood-thinners

Mayo Clinic: https://www.mayoclinic.org/diseases-conditions/deep-vein-thrombosis/symptoms-causes/syc-20352581