Glipizide

A sulfonylurea drug that stimulates the pancreas to release more insulin.

Metformin

A biguanide drug that helps to improve insulin sensitivity and decreases glucose production by the liver.

Type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

Glipizide works by increasing insulin secretion from the pancreas, while metformin works by reducing glucose production in the liver and improving insulin sensitivity in the body's tissues. The combination enhances blood sugar control by acting on different aspects of glucose metabolism.

Store at room temperature, away from moisture and heat. Keep out of reach of children.

Dosage is determined by your doctor based on your individual needs and response to treatment.

Follow your doctor's instructions carefully. Do not change your dose or stop taking the medication without consulting your doctor.

Typically taken with meals to reduce gastrointestinal side effects.

Hypoglycemia (low blood sugar): Symptoms include dizziness, sweating, shakiness, and confusion.

Lactic acidosis (rare but serious): Characterized by fatigue, muscle pain, and difficulty breathing. Seek immediate medical attention if you suspect this.

Gastrointestinal upset (nausea, vomiting, diarrhea)

Weight gain

Allergic reactions (rash, itching, swelling)

Alcohol Consumption

Alcohol can increase the risk of hypoglycemia and lactic acidosis. Limit alcohol intake while taking this medication.



While Driving or operating Machinery

Hypoglycemia can impair your ability to drive or operate machinery. Avoid these activities if you experience symptoms of low blood sugar.



Pregnant & Breastfeeding Women

Not recommended during pregnancy or breastfeeding. Discuss alternative treatments with your doctor.



Children

Not typically used in children.



Kidney

Dosage adjustments may be necessary for patients with kidney disease.



Liver

Caution is advised for patients with liver disease.

Your doctor or pharmacist

The medication's package insert

Reputable medical websites (e.g., Mayo Clinic, NHS)