Prescription Required.
Cefotaxime sodium (as the active ingredient)Various inactive ingredients depending on the formulation (e.g., sodium chloride, water for injection)
Treatment of bacterial infections caused by susceptible organisms in various parts of the body, including:
Lower respiratory tract infections (e.g., pneumonia)
Intraabdominal infections (e.g., peritonitis)
Gynecological infections (e.g., pelvic inflammatory disease)
Bacterial meningitis
Septicemia
Skin and soft tissue infections
Bone and joint infections
Bestax Inj 1gm (Cefotaxime) is a broad-spectrum cephalosporin antibiotic. It works by inhibiting bacterial cell wall synthesis, thereby preventing bacterial growth and ultimately leading to bacterial cell death. It achieves this by binding to penicillin-binding proteins (PBPs), essential enzymes involved in the final stages of peptidoglycan synthesis.
Store at controlled room temperature (20°C to 25°C). Protect from light and moisture. Discard any unused portion after the expiry date.
Dosage and frequency depend on the severity of the infection, the patient's age and kidney function, and the specific infecting organism.
Cefotaxime is usually administered intravenously or intramuscularly.
Always follow your doctor's prescribed dosage and administration instructions meticulously.
In rare cases: severe allergic reactions (anaphylaxis), seizures
Nausea
Vomiting
Diarrhea
Abdominal pain
Rash
Itching
Headache
Dizziness
Elevated liver enzymes
Clostridium difficileassociated diarrhea (CDAD)
Alcohol consumption may exacerbate certain side effects, especially nausea and vomiting. Consult your physician regarding alcohol consumption while taking Cefotaxime.
Cefotaxime may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how it affects you.
Cefotaxime should only be used during pregnancy or breastfeeding if the potential benefits outweigh the potential risks. Consult your physician.
Dosage adjustments are necessary for children based on weight and age. Consult a pediatrician.
Dosage adjustment is necessary for patients with impaired kidney function. Your doctor will monitor your kidney function during treatment.
Cefotaxime can affect liver function; liver function tests are often monitored during therapy. Patients with pre-existing liver disease may require special monitoring.
Your doctor or pharmacist
The prescribing information provided by the manufacturer
Reputable medical websites and journals (e.g., Mayo Clinic, UpToDate)
