Atacurium Inj 10ml: Price, Use, Benefit, Side Effect

Atacurium Inj 10ml

Prescription Required.Why?

Marketer

Themis Medicare Ltd

Composition

Atracurium Besylate (100mg/10ml)

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About Atacurium Inj 10ml

Atacurium Inj 10ml (Atracurium Besylate) is a short-acting muscle relaxant used during surgery and mechanical ventilation. It works by blocking nerve signals to muscles. While generally safe, potential side effects include hypotension and tachycardia. It's crucial to follow your doctor's instructions carefully and inform them of any pre-existing medical conditions. Driving and alcohol consumption should be avoided until fully recovered. The drug is metabolized outside the liver and kidneys, making it suitable for patients with those conditions.

Ingredients

Directions for Use

How Drug Works

Storage & Handling

Drug Dosage

Side Effects

Safety Consideration or Warnings

References

Ingredients of Atacurium Inj 10ml

Atracurium Besylate

Is the active ingredient.

Direction for Use of Atacurium Inj 10ml

Shortterm neuromuscular blockade during surgery or mechanical ventilation.

Facilitating endotracheal intubation.

Relaxing skeletal muscles during surgical procedures.

How Atacurium Inj 10ml Works

Atacurium Inj 10ml (Atracurium Besylate) acts as a non-depolarizing neuromuscular blocking agent. It competitively binds to nicotinic acetylcholine receptors at the neuromuscular junction, preventing the action of acetylcholine and thus causing muscle relaxation. It is rapidly metabolized by Hofmann elimination and ester hydrolysis, avoiding the need for hepatic or renal metabolism.

Storage and Handling of Atacurium Inj 10ml

Store at controlled room temperature 20°C to 25°C (68°F to 77°F) [See USP]. Protect from light. Dispose of unused medication according to local regulations. Do not freeze.

Dosage of Atacurium Inj 10ml

Dosage is determined by the physician based on individual patient needs, age, weight, and other factors.

Administration is typically intravenous.

Precise dosage and administration guidelines must be followed as prescribed by a qualified healthcare professional.

Side effects of Atacurium Inj 10ml

Hypotension

Tachycardia

Bronchospasm (rare but potentially serious)

Muscle weakness (postoperative)

Malignant hyperthermia (rare, but serious)

Allergic reactions (rare)

Safety Consideration or Warnings

Alcohol Consumption

The effects of alcohol and atracurium besylate are not well-studied, but it is generally advised to avoid alcohol consumption before or after surgery requiring this medication.

Driving or operating Machinery

Patients should not drive or operate machinery until the effects of the medication have completely worn off and they are fully alert and recovered.

Pregnant & Breastfeeding Women

Atracurium besylate should only be used during pregnancy or breastfeeding if the benefits clearly outweigh the potential risks. Discuss with your doctor before use.

Children

Dosage adjustments are necessary for children; it should only be administered under strict medical supervision.

Kidney

Renal impairment generally does not require dosage adjustment because atracurium is not significantly eliminated by the kidneys.

Liver

Hepatic impairment does not significantly impact atracurium metabolism due to its non-hepatic metabolism.

References

Physician's Desk Reference (PDR)

Product monograph provided by the manufacturer.

Last Updated On 31 Dec. 2025 | 12:37 PM (IST)

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