, also known as acenocoumarol, is the active ingredient in this medication.
Prevention and treatment of blood clots (thromboembolic disorders) such as:
Deep vein thrombosis (DVT)
Pulmonary embolism (PE)
Atrial fibrillation (AFib) with a high risk of stroke
Prevention of blood clots after certain surgeries or medical procedures.
Artiflo 3mg Tab (Nicoumalone) is an anticoagulant medication. It works by interfering with the production of certain clotting factors in the liver. This makes the blood thinner and less likely to clot. It is classified as a vitamin K antagonist, as it works by blocking the action of vitamin K, a vital component in blood clotting.
Store nicoumalone tablets at room temperature, away from light and moisture. Keep out of reach of children and pets.
The dosage of nicoumalone is individualized and depends on various factors including your medical history, age, and the condition being treated.
Your doctor will determine the appropriate starting dose and adjust it based on regular blood tests (INR - International Normalized Ratio) to ensure proper blood thinning.
Nicoumalone tablets should be taken orally with or without food.
Do not crush, chew, or break the tablets.
Always follow your doctor's instructions carefully and take the medication exactly as prescribed.
Common side effects:
Bleeding from the nose, gums, or stomach
Serious side effects (rare but may be life-threatening):
Bruising easily
Skin rash
Diarrhea
Nausea
Vomiting
Excessive bleeding (internal or external)
Stroke
Liver damage
Alcohol can increase the risk of bleeding while taking nicoumalone. Limit or avoid alcohol consumption.
Nicoumalone can cause dizziness, fatigue, or drowsiness. Avoid driving or operating machinery until you know how the medication affects you.
Nicoumalone is not recommended for use during pregnancy, as it can cause harm to the fetus. It may also pass into breast milk, so consult your doctor before breastfeeding while taking nicoumalone.
Nicoumalone is not approved for use in children.
Kidney and liver disease can affect how nicoumalone is processed in the body. Your doctor may need to adjust your dose or monitor you closely.
Your doctor or pharmacist
Medication package insert
Manufacturer's website
National Institutes of Health (NIH)
Food and Drug Administration (FDA)
