Glucosamine is a naturally occurring compound found in cartilage, the tough, flexible tissue that cushions joints.
Methylsulfonylmethane (MSM) is a naturally occurring sulfur-containing compound found in many foods and supplements.
Glucosamine and MSM are often combined in supplements to support joint health.
Osteoarthritis: Glucosamine and MSM may help reduce pain and improve function in people with osteoarthritis.
Joint pain and stiffness: This combination may provide relief from joint pain and stiffness associated with various conditions.
Inflammation: Both glucosamine and MSM have anti-inflammatory properties that may help reduce inflammation in the joints.
0 Glucosamine: Glucosamine is thought to help stimulate the production of cartilage, which may help repair and maintain joint health.1 MSM: MSM is a source of sulfur, which is an essential component of cartilage and connective tissue. MSM may also have anti-inflammatory effects.2 Combined Effect: The combination of glucosamine and MSM may provide a synergistic effect, enhancing their individual benefits on joint health.
Store in a cool, dry place, away from direct sunlight and moisture.
Keep out of reach of children.
Follow the dosage instructions provided by your doctor or on the product label.
Typical dosage for glucosamine and MSM supplements ranges from 1,500 to 3,000 milligrams per day, taken in divided doses.
It is important to take the supplements with food to help improve absorption.
Allergic reactions: Skin rash, itching, or swelling.
Gastrointestinal: Nausea, heartburn, diarrhea, or constipation.
Other: Headaches, dizziness, or drowsiness.
It is generally safe to consume alcohol while taking glucosamine and MSM, but excessive alcohol intake can negatively affect liver function and may interfere with the absorption of these supplements.
Glucosamine and MSM are not known to affect mental alertness or motor skills, but it is always important to exercise caution when driving or operating machinery, especially if you experience any side effects such as drowsiness.
There is limited research on the safety of glucosamine and MSM during pregnancy and breastfeeding. It is best to consult with your healthcare provider before taking these supplements if you are pregnant or breastfeeding.
The safety and efficacy of glucosamine and MSM in children have not been established. Do not give these supplements to children without consulting a doctor.
People with kidney or liver problems should consult their doctor before taking glucosamine and MSM. These supplements may put additional strain on these organs.
National Institutes of Health (NIH) Office of Dietary Supplements
American Academy of Orthopaedic Surgeons (AAOS)
National Center for Complementary and Integrative Health (NCCIH)
