The active form of vitamin b12. it's more readily absorbed and utilized by the body compared to cyanocobalamin.
The active form of vitamin b6. it's directly involved in enzymatic reactions, unlike pyridoxine (b6's inactive form).
Treatment of vitamin B9, B12, and B6 deficiencies.
Support for neurological function in conditions like peripheral neuropathy.
Management of certain types of anemia.
Support for cognitive function (often used in combination with other therapies).
May be used to reduce homocysteine levels (high levels are associated with cardiovascular risk, but this is not a primary indication).
These three B vitamins work synergistically in various metabolic pathways. L-methylfolate and methylcobalamin are crucial in the methylation cycle, a vital process affecting DNA synthesis, neurotransmitter production, and homocysteine metabolism. Pyridoxal-5-phosphate is a coenzyme for many enzymes involved in amino acid metabolism, neurotransmitter synthesis, and the conversion of homocysteine.
Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Dosage varies depending on individual needs and the specific product formulation. Always follow the instructions provided by your healthcare professional or the product labeling.
The medication may be taken with or without food.
Mild gastrointestinal upset (nausea, diarrhea).
Allergic reactions (rash, itching, swelling).
Excessive alcohol consumption can interfere with the absorption and utilization of B vitamins. Moderate alcohol consumption might be acceptable but consult with your doctor.
Generally considered safe unless side effects like dizziness or nausea occur. Follow your doctor's advice.
Consult your doctor before use during pregnancy or breastfeeding. While generally considered safe at appropriate doses, specific recommendations are needed.
Dosage needs to be adjusted based on age and weight. Always consult a pediatrician.
Individuals with kidney disease should use caution and discuss dosage with their nephrologist.
Patients with liver disease should use caution and discuss dosage with their hepatologist.
Medical journals and textbooks on nutrition and hematology (specific citations would require extensive research and would vary based on specific claims being made).
Product inserts of specific brands containing this formulation (these vary based on the manufacturer).
