Prescription Required.Why?
Hydrochloride
Treatment of major depressive disorder (MDD)
Treatment of neuropathic pain (nerve pain)
Treatment of anxiety disorders (in some cases, may be used as an adjunct)
Treatment of enuresis (bedwetting) in children (offlabel use, requires careful consideration by physician)
Amitriptyline Hydrochloride Tablets Ip 10mg (Amitriptyline) is a tricyclic antidepressant (TCA). It works primarily by blocking the reuptake of serotonin and norepinephrine in the brain, increasing the levels of these neurotransmitters and improving mood, sleep, and pain perception. The exact mechanisms contributing to its effectiveness in different conditions are not fully elucidated.
Store at room temperature away from moisture and direct sunlight. Keep out of reach of children and pets. Discard any unused medication after the expiration date.
Dosage is determined by a physician based on individual needs and condition.
Dosage is usually started low and gradually increased as tolerated.
Take exactly as prescribed; do not alter the dose or frequency without consulting a doctor.
Swallow tablets whole with water; do not crush or chew.
It may take several weeks to see the full therapeutic effect.
Drowsiness or sedation
Dry mouth
Constipation
Blurred vision
Orthostatic hypotension (dizziness upon standing)
Weight gain
Sexual dysfunction
Increased heart rate
Anticholinergic effects (e.g., urinary retention)
Alcohol should be avoided or consumed very sparingly while taking amitriptyline, as it can potentiate sedative effects.
Avoid driving or operating machinery until you know how amitriptyline affects you. Drowsiness is a common side effect.
Amitriptyline should only be used during pregnancy or breastfeeding if the potential benefits outweigh the risks to the fetus or infant. Consult your doctor.
Use in children is limited to specific conditions (e.g., enuresis) and requires careful monitoring by a physician. It is not generally used for depression in children.
Dosage adjustments may be necessary in patients with impaired kidney function.
Dosage adjustments may be necessary in patients with impaired liver function.
Your doctor or pharmacist
The prescribing information for the specific amitriptyline product you are taking.
Reputable medical websites (e.g., Mayo Clinic, NHS)
