Prescription Required.
Buprenorphine is an opioid partial agonist.Different formulations may include naloxone (to deter misuse by injection).
Treatment of opioid use disorder (OUD).
Management of moderate to severe chronic pain in certain situations, but generally not preferred over other analgesics due to the risk of addiction.
Addnok 0.2mg Tab (Buprenorphine) binds to opioid receptors in the brain, reducing opioid cravings and withdrawal symptoms. Its partial agonist activity means it produces a weaker opioid effect than full agonists like heroin or morphine, reducing the risk of overdose. Naloxone, if present, blocks opioid effects if injected but is not absorbed when taken orally.
Store at room temperature, away from moisture and heat. Keep out of reach of children and pets. Dispose of unused medication properly according to instructions.
Dosage is determined by a healthcare professional and is highly individualized based on the patient's condition and response to treatment.
Buprenorphine is usually administered orally (sublingual or buccal) or via implant.
Never abruptly stop taking buprenorphine without consulting a doctor.
Follow your doctor's instructions carefully regarding the dosage and timing of your medication.
Constipation
Nausea
Vomiting
Dizziness
Headache
Sleepiness
Sweating
Withdrawal symptoms (if abruptly stopped)
Serious allergic reactions (rare)
Alcohol should be avoided while taking buprenorphine as it can increase the risk of drowsiness and respiratory depression.
Avoid driving or operating machinery until you know how buprenorphine affects you. Drowsiness is a common side effect.
Use during pregnancy or breastfeeding should only occur under the close supervision of a healthcare professional. Risks to the fetus or infant should be carefully weighed against the benefits.
Buprenorphine is not typically prescribed for children. Use in children should only be considered in exceptional circumstances and under strict medical supervision.
Patients with kidney impairment may require dose adjustments.
Patients with liver impairment may require dose adjustments.
Your doctor or pharmacist
The FDA website (www.fda.gov)
Reputable medical journals and websites (e.g., PubMed)
