A sulfonylurea drug that stimulates the pancreas to release more insulin.
A biguanide that improves insulin sensitivity and reduces glucose production by the liver.
A thiazolidinedione (tzd) that improves insulin sensitivity by acting on cells' insulin receptors.
Type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.
Used in patients who need multiple medications to manage their blood sugar effectively.
This combination drug works through three different mechanisms to lower blood glucose levels. Glimepiride stimulates insulin release from the pancreas. Metformin reduces glucose production in the liver and increases insulin sensitivity in peripheral tissues. Pioglitazone enhances insulin sensitivity by improving the way cells respond to insulin.
Store at room temperature (below 25°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Dosage is determined by your doctor based on your individual needs and response to treatment. It's crucial to follow your physician's prescribed dosage and timing.
This medication is typically taken orally with meals to minimize gastrointestinal side effects.
Hypoglycemia (low blood sugar): Symptoms may include sweating, dizziness, shakiness, and confusion.
Gastrointestinal upset: Nausea, vomiting, diarrhea, and abdominal pain.
Weight gain (especially with pioglitazone)
Fluid retention
Allergic reactions (rash, itching, swelling)
Alcohol can increase the risk of hypoglycemia. Limit alcohol intake while taking this medication.
Hypoglycemia can impair judgment and reaction time. Avoid driving or operating machinery if you experience hypoglycemic symptoms.
Generally not recommended during pregnancy and breastfeeding. Consult your doctor before use.
Not typically recommended for use in children.
Dosage adjustments may be necessary for individuals with kidney problems.
Regular monitoring of liver function is recommended due to the risk of liver problems with pioglitazone.
Your doctor or pharmacist.
The product monograph provided with your medication.
Reputable medical websites (e.g., those of government health organizations).
