Adapalene

A retinoid that helps to unclog pores, reduce inflammation, and prevent the formation of acne lesions.

Clindamycin

An antibiotic that kills bacteria that contribute to acne development.

Treatment of inflammatory acne vulgaris (acne with papules and pustules)

Reduces the number of acne lesions and improves the appearance of the skin.

Adapalene works by regulating cell turnover and reducing inflammation, while clindamycin directly combats the bacteria (like Cutibacterium acnes) that contribute to acne. The combination provides a synergistic effect, addressing both inflammation and bacterial infection.

Store at room temperature (20°C-25°C), away from direct sunlight and moisture. Keep out of reach of children.

Apply a thin layer to the affected area once daily, usually in the evening.

Wash and dry the affected skin before applying.

Avoid contact with eyes, mouth, and other mucous membranes.

Start with less frequent application initially to assess skin tolerance.

Follow your doctor's or dermatologist's instructions carefully.

Increased sun sensitivity

Itching

Rare cases of allergic reactions

Alcohol Consumption

No specific contraindications, but excessive alcohol consumption can exacerbate skin conditions. Consult your doctor.



Driving or Operating Machinery

Generally safe, but if side effects like dizziness or blurred vision occur, avoid operating machinery.



Pregnant & Breastfeeding Women

Consult your doctor before use as the safety of adapalene and clindamycin during pregnancy and breastfeeding has not been established fully. It may not be suitable.



Children

Use in children should only be under the supervision of a dermatologist. Not generally recommended.



Kidney

Generally safe for individuals with normal kidney function.



Liver

Generally safe for individuals with normal liver function.

Your doctor or dermatologist

Medication package insert

Reputable medical websites (e.g., Mayo Clinic, NHS)